EOMES
Information EOMES
- Description
Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. {ECO:0000269|PubMed:10716450, ECO:0000269|PubMed:14605368, ECO:0000269|PubMed:18171685, ECO:0000269|PubMed:18940588}.(Source UnitProtKB).
- Full Name
eomesodermin
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 5
- Peaks
- 34,557
- Non-redundant peaks
- 34,439
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 13813
- Official Gene Name
- Eomes
- JASPAR
- MGI
- MGI:1201683
- Ensembl
- ENSMUSG00000032446
- UniProt
- O54839
- Genevisible
- O54839
- RefSeq
- NM_010136
- Aliases
- C77258; TBR-2; Tbr2
Datasets Table for EOMES
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| EOMES | cortex | GEO | Mus musculus | GSE63620 | 14,611 | |||
| EOMES | trophoblast-stem-cell | paired-end | GEO | Mus musculus | GSE42207 | 16,473 | ||
| EOMES | EBs | dKO | GEO | Mus musculus | GSE128466 | 226 | ||
| EOMES | TSC | GEO | Mus musculus | GSE110950 | 639 | |||
| EOMES | spleen | GEO | Mus musculus | GSE122888 | 2,608 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |