HMGB2

Information HMGB2

Description

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]

Full Name

high mobility group box 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
3
Biotypes
2
Peaks
25,093
Non-redundant peaks
23,158

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3148
Official Gene Name
HMGB2
JASPAR
Ensembl
ENSG00000164104
UniProt
P26583
Genevisible
P26583
RefSeq
NM_001130688
Aliases
HMG2
All peaks HMGB2
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Non redundant peaks HMGB2
Download BED file
SEQUENCES HMGB2
Download FASTA file
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Datasets Table for HMGB2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HMGB2 IMR-90 senescent GEO Homo sapiens GSE98245 782
HMGB2 IMR-90 proliferating GEO Homo sapiens GSE98245 6,768
HMGB2 HUVEC-C GEO Homo sapiens GSE98245 17,543
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks