ISL1

Information ISL1

Description

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

Full Name

ISL LIM homeobox 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
3
Biotypes
3
Peaks
60,572
Non-redundant peaks
60,484

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3670
Official Gene Name
ISL1
JASPAR
Ensembl
ENSG00000016082
UniProt
P61371
Genevisible
P61371
RefSeq
NM_002202
Aliases
ISLET1; Isl-1
All peaks ISL1
Download BED file
Non redundant peaks ISL1
Download BED file
SEQUENCES ISL1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for ISL1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ISL1 A2780 cisplatin GEO Homo sapiens GSE129700 149
ISL1 Huh-7 GEO Homo sapiens GSE77957 5,353
ISL1 SK-N-BE2-C GEO Homo sapiens GSE94822 55,070
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks