MRTFA

Information MRTFA

Description

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Full Name

myocardin related transcription factor A

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
10,865
Non-redundant peaks
10,865

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
57591
Official Gene Name
MRTFA
JASPAR
Ensembl
ENSG00000196588
UniProt
Q969V6
Genevisible
Q969V6
RefSeq
NM_001282660
Aliases
BSAC; KIAA1438; MAL; MKL; MRTF-A
All peaks MRTFA
Download BED file
Non redundant peaks MRTFA
Download BED file
SEQUENCES MRTFA
Download FASTA file
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Datasets Table for MRTFA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MRTFA A-673-clone-Asp114 GEO Homo sapiens GSE92738 10,865
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks