NCOR2

Information NCOR2

Description

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]

Full Name

nuclear receptor corepressor 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
4
Peaks
90,910
Non-redundant peaks
77,230

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
9612
Official Gene Name
NCOR2
JASPAR
Ensembl
ENSG00000196498
UniProt
Q9Y618
Genevisible
Q9Y618
RefSeq
NM_001077261
Aliases
CTG26; N-CoR2; SMAP270; SMRT; SMRTE; SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1
All peaks NCOR2
Download BED file
Non redundant peaks NCOR2
Download BED file
SEQUENCES NCOR2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for NCOR2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NCOR2 OCI-Ly1 GEO Homo sapiens GSE29282 7,713
NCOR2 LS180 125 GEO Homo sapiens GSE39277 29,423
NCOR2 LS180 GEO Homo sapiens GSE39277 17,156
NCOR2 AML shaml1-eto GEO Homo sapiens GSE131939 17,021
NCOR2 AML GEO Homo sapiens GSE131939 9,078
NCOR2 B-cell GERMINAL_CENTER GEO Homo sapiens GSE43350 10,519
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks