NFKBIA

Information NFKBIA

Description

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Full Name

NFKB inhibitor alpha

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
1,786
Non-redundant peaks
1,786

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
4792
Official Gene Name
NFKBIA
JASPAR
Ensembl
ENSG00000100906
UniProt
P25963
Genevisible
P25963
RefSeq
NM_020529
Aliases
EDAID2; IKBA; IkappaBalpha; MAD-3; NFKBI
All peaks NFKBIA
Download BED file
Non redundant peaks NFKBIA
Download BED file
SEQUENCES NFKBIA
Download FASTA file
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Datasets Table for NFKBIA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NFKBIA dermal GEO Homo sapiens GSE30082 1,786
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks