PRDM2

Information PRDM2

Description

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Full Name

PR/SET domain 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
772
Non-redundant peaks
772

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7799
Official Gene Name
PRDM2
JASPAR
Ensembl
ENSG00000116731
UniProt
Q13029
Genevisible
Q13029
RefSeq
NM_001007257
Aliases
HUMHOXY1; KMT8; KMT8A; MTB-ZF; RIZ; RIZ1; RIZ2
All peaks PRDM2
Download BED file
Non redundant peaks PRDM2
Download BED file
SEQUENCES PRDM2
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for PRDM2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PRDM2 HEK293 ENCODE Homo sapiens ENCSR714LYA 772
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks