SMARCA2
Information SMARCA2
- Description
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
- Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 10
- Biotypes
- 2
- Peaks
- 209,617
- Non-redundant peaks
- 89,655
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 6595
- Official Gene Name
- SMARCA2
- JASPAR
- Ensembl
- ENSG00000080503
- UniProt
- P51531
- Genevisible
- P51531
- RefSeq
- NM_001289396
- Aliases
- BAF190; BRM; NCBRS; SNF2; SNF2L2; SNF2LA; SWI2; Sth1p; hBRM; hSNF2a
Datasets Table for SMARCA2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SMARCA2 | SK-N-MC | shGFP | GEO | Homo sapiens | GSE94275 | 3,567 | ||
| SMARCA2 | SK-N-MC | shEWSFLI1 | GEO | Homo sapiens | GSE94275 | 15,919 | ||
| SMARCA2 | NPC | K755R-pos_ab | GEO | Homo sapiens | GSE122631 | 15,895 | ||
| SMARCA2 | NPC | R1159Q_ab | GEO | Homo sapiens | GSE122631 | 8,120 | ||
| SMARCA2 | NPC | K755R-pos | GEO | Homo sapiens | GSE122631 | 40,571 | ||
| SMARCA2 | NPC | R1159Q | GEO | Homo sapiens | GSE122631 | 17,756 | ||
| SMARCA2 | NPC | AM | GEO | Homo sapiens | GSE122631 | 17,028 | ||
| SMARCA2 | NPC | K755R-siCT | GEO | Homo sapiens | GSE122631 | 39,439 | ||
| SMARCA2 | NPC | R1159Q_AM | GEO | Homo sapiens | GSE122631 | 27,012 | ||
| SMARCA2 | NPC | K755R-siAP | GEO | Homo sapiens | GSE122631 | 24,310 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |