TRIM25

Information TRIM25

Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]

Full Name

tripartite motif containing 25

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
2
Peaks
47,535
Non-redundant peaks
47,535

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7706
Official Gene Name
TRIM25
JASPAR
Ensembl
ENSG00000121060
UniProt
Q14258
Genevisible
Q14258
RefSeq
NM_005082
Aliases
EFP; RNF147; Z147; ZNF147
All peaks TRIM25
Download BED file
Non redundant peaks TRIM25
Download BED file
SEQUENCES TRIM25
Download FASTA file
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Datasets Table for TRIM25

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TRIM25 BT-549 GEO Homo sapiens GSE79588 31,156
TRIM25 MDA-MB-231 GEO Homo sapiens GSE79588 16,379
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks