USP7

Information USP7

Description

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]

Full Name

ubiquitin specific peptidase 7

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
8,854
Non-redundant peaks
8,854

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7874
Official Gene Name
USP7
JASPAR
Ensembl
ENSG00000187555
UniProt
Q93009
Genevisible
Q93009
RefSeq
NM_001286457
Aliases
HAUSP; TEF1
All peaks USP7
Download BED file
Non redundant peaks USP7
Download BED file
SEQUENCES USP7
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for USP7

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
USP7 HEK293T GEO Homo sapiens GSE61048 8,854
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks