ARNTL

Information ARNTL

Description

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Full Name

aryl hydrocarbon receptor nuclear translocator like

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
15
Biotypes
5
Peaks
201,872
Non-redundant peaks
130,321

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
406
Official Gene Name
ARNTL
JASPAR
Ensembl
ENSG00000133794
UniProt
O00327
Genevisible
O00327
RefSeq
NM_001030272
Aliases
BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC; bHLHe5
All peaks ARNTL
Download BED file
Non redundant peaks ARNTL
Download BED file
SEQUENCES ARNTL
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for ARNTL

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ARNTL Hep-G2 ENCODE Homo sapiens ENCSR794LVK 30,878
ARNTL SK-N-SH all-trans-retinoic-acid_6-uM_48-hour ENCODE Homo sapiens ENCSR949COJ 1,180
ARNTL U2OS DMSO GEO Homo sapiens GSE130506 13,943
ARNTL U2OS GEO Homo sapiens GSE130602 13,929
ARNTL U2OS cordycepin GEO Homo sapiens GSE130506 10,033
ARNTL U2OS trough_DMSO GEO Homo sapiens GSE85096 8,086
ARNTL U2OS trough_DMOG GEO Homo sapiens GSE85096 17,966
ARNTL U2OS DMOG GEO Homo sapiens GSE85096 32,014
ARNTL U2OS GEO Homo sapiens GSE69100 278
ARNTL U2OS DMSO GEO Homo sapiens GSE85096 12,210
ARNTL U2OS GEO Homo sapiens GSE44236 20,739
ARNTL NSC ENSA GEO Homo sapiens GSE134972 300
ARNTL NSC hNP1 GEO Homo sapiens GSE134972 12,294
ARNTL GSC 387 GEO Homo sapiens GSE134972 14,631
ARNTL GSC 3565 GEO Homo sapiens GSE134972 13,391
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks