ARNTL
Information ARNTL
- Description
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
- Full Name
aryl hydrocarbon receptor nuclear translocator like
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 15
- Biotypes
- 5
- Peaks
- 201,872
- Non-redundant peaks
- 130,321
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 406
- Official Gene Name
- ARNTL
- JASPAR
- Ensembl
- ENSG00000133794
- UniProt
- O00327
- Genevisible
- O00327
- RefSeq
- NM_001030272
- Aliases
- BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC; bHLHe5
Datasets Table for ARNTL
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ARNTL | Hep-G2 | ENCODE | Homo sapiens | ENCSR794LVK | 30,878 | |||
| ARNTL | SK-N-SH | all-trans-retinoic-acid_6-uM_48-hour | ENCODE | Homo sapiens | ENCSR949COJ | 1,180 | ||
| ARNTL | U2OS | DMSO | GEO | Homo sapiens | GSE130506 | 13,943 | ||
| ARNTL | U2OS | GEO | Homo sapiens | GSE130602 | 13,929 | |||
| ARNTL | U2OS | cordycepin | GEO | Homo sapiens | GSE130506 | 10,033 | ||
| ARNTL | U2OS | trough_DMSO | GEO | Homo sapiens | GSE85096 | 8,086 | ||
| ARNTL | U2OS | trough_DMOG | GEO | Homo sapiens | GSE85096 | 17,966 | ||
| ARNTL | U2OS | DMOG | GEO | Homo sapiens | GSE85096 | 32,014 | ||
| ARNTL | U2OS | GEO | Homo sapiens | GSE69100 | 278 | |||
| ARNTL | U2OS | DMSO | GEO | Homo sapiens | GSE85096 | 12,210 | ||
| ARNTL | U2OS | GEO | Homo sapiens | GSE44236 | 20,739 | |||
| ARNTL | NSC | ENSA | GEO | Homo sapiens | GSE134972 | 300 | ||
| ARNTL | NSC | hNP1 | GEO | Homo sapiens | GSE134972 | 12,294 | ||
| ARNTL | GSC | 387 | GEO | Homo sapiens | GSE134972 | 14,631 | ||
| ARNTL | GSC | 3565 | GEO | Homo sapiens | GSE134972 | 13,391 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |