BCL3

Information BCL3

Description

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]

Full Name

BCL3 transcription coactivator

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
2
Peaks
75,697
Non-redundant peaks
71,827

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
602
Official Gene Name
BCL3
JASPAR
Ensembl
ENSG00000069399
UniProt
P20749
Genevisible
P20749
RefSeq
NM_005178
Aliases
BCL4; D19S37
All peaks BCL3
Download BED file
Non redundant peaks BCL3
Download BED file
SEQUENCES BCL3
Download FASTA file
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Datasets Table for BCL3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
BCL3 A-549 ENCODE Homo sapiens ENCSR000BQH 37,934
BCL3 GM12878 ENCODE Homo sapiens ENCSR000BNQ 37,763
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks