BRD2

Information BRD2

Description

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]

Full Name

bromodomain containing 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
57
Biotypes
13
Peaks
1,661,001
Non-redundant peaks
309,405

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6046
Official Gene Name
BRD2
JASPAR
Ensembl
ENSG00000236227
UniProt
P25440
Genevisible
P25440
RefSeq
NM_001113182
Aliases
BRD2-IT1; D6S113E; FSH; FSRG1; KIAA9001; NAT; O27.1.1; RING3; RNF3

External links
All peaks BRD2
Download BED file
Non redundant peaks BRD2
Download BED file
SEQUENCES BRD2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for BRD2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
BRD2 SK-MEL-147 GEO Homo sapiens GSE94488 79,065
BRD2 SK-MEL-147 JQ1 GEO Homo sapiens GSE94488 62,196
BRD2 HCC1806 NTsiRNA_JQ1 GEO Homo sapiens GSE116879 31,907
BRD2 HCC1806 NTsiRNA GEO Homo sapiens GSE116879 50,300
BRD2 HCC1806 BAZ2B_JQ1 GEO Homo sapiens GSE116879 33,696
BRD2 HCC1806 BAZ2BsiRNA GEO Homo sapiens GSE116879 50,092
BRD2 MV4-11 IBET151_50nM GEO Homo sapiens GSE120715 11,818
BRD2 MV4-11 DMSO GEO Homo sapiens GSE120715 4,078
BRD2 MV4-11 IBET151_500nM GEO Homo sapiens GSE120715 37,482
BRD2 THP-1 DMSO GEO Homo sapiens GSE138084 26,116
BRD2 THP-1 iBET-BD2 GEO Homo sapiens GSE138084 25,235
BRD2 THP-1 iBET-BD1 GEO Homo sapiens GSE138084 29,954
BRD2 THP-1 iBET-BD2-PMA GEO Homo sapiens GSE138084 3,616
BRD2 THP-1 DMSO-PMA GEO Homo sapiens GSE138084 5,977
BRD2 THP-1 iBET GEO Homo sapiens GSE138084 34,816
BRD2 SUM149PT R_JQ1 GEO Homo sapiens GSE131097 24,686
BRD2 SUM149PT JQ1 GEO Homo sapiens GSE131097 27,714
BRD2 SUM149PT R_DMSO GEO Homo sapiens GSE131097 24,780
BRD2 SUM149PT DMSO GEO Homo sapiens GSE131097 30,037
BRD2 K-562 GEO Homo sapiens GSE140325 40,079
BRD2 K-562 DMSO GEO Homo sapiens GSE138084 29,003
BRD2 K-562 DMSO-IFNG GEO Homo sapiens GSE138084 22,800
BRD2 K-562 IBET151_5000nM GEO Homo sapiens GSE120715 1,600
BRD2 K-562 IBET151_50nM GEO Homo sapiens GSE120715 8,638
BRD2 K-562 iBET-BD2-IFNG GEO Homo sapiens GSE138084 15,600
BRD2 K-562 DMSO GEO Homo sapiens GSE120715 3,985
BRD2 K-562 IBET151_500nM GEO Homo sapiens GSE120715 1,728
BRD2 K-562 dilution-6-100 GEO Homo sapiens GSE140325 19,410
BRD2 K-562 iBET-BD1-IFNG GEO Homo sapiens GSE138084 15,515
BRD2 K-562 iBET-IFNG GEO Homo sapiens GSE138084 22,011
BRD2 MDA-MB-231 JQ1_rDNA GEO Homo sapiens GSE116879 50,059
BRD2 MDA-MB-231 BAZ2AsiRNA_JQ1 GEO Homo sapiens GSE116879 33,527
BRD2 MDA-MB-231 NTsiRNA GEO Homo sapiens GSE116879 46,835
BRD2 MDA-MB-231 NTsiRNA_JQ1 GEO Homo sapiens GSE116879 42,819
BRD2 MDA-MB-231 BAZ2AsiRNA GEO Homo sapiens GSE116879 41,193
BRD2 MDA-MB-231 JQ1 GEO Homo sapiens GSE116879 50,087
BRD2 MDA-MB-231 DMSO_rDNA GEO Homo sapiens GSE116879 24,662
BRD2 MDA-MB-231 JQ1_MGSK2801 GEO Homo sapiens GSE116879 45,054
BRD2 MDA-MB-231 MGSK2801_rDNA GEO Homo sapiens GSE116879 50,489
BRD2 MDA-MB-231 DMSO GEO Homo sapiens GSE116879 24,644
BRD2 MDA-MB-231 BAZ2BsiRNA_JQ1 GEO Homo sapiens GSE116879 21,417
BRD2 MDA-MB-231 MGSK2801 GEO Homo sapiens GSE116879 50,505
BRD2 MDA-MB-231 BAZ2BsiRNA GEO Homo sapiens GSE116879 47,829
BRD2 MDA-MB-231 JQ1_MGSK2801_rDNA GEO Homo sapiens GSE116879 45,041
BRD2 HUVEC-C GEO Homo sapiens GSE60171 10,803
BRD2 HUVEC-C MS417 GEO Homo sapiens GSE60171 332
BRD2 NCI-H23 GEO Homo sapiens GSE113714 18,821
BRD2 NCI-H23 GEO Homo sapiens GSE104481 15,855
BRD2 LPS141 GEO Homo sapiens GSE111253 11,294
BRD2 SUM159PT R_JQ1 GEO Homo sapiens GSE131097 6,634
BRD2 SUM159PT JQ1 GEO Homo sapiens GSE116879 40,580
BRD2 SUM159PT JQ1_MGSK2801 GEO Homo sapiens GSE116879 45,597
BRD2 SUM159PT MGSK2801 GEO Homo sapiens GSE116879 71,439
BRD2 SUM159PT DMSO GEO Homo sapiens GSE116879 55,277
BRD2 SUM159PT DMSO GEO Homo sapiens GSE131097 14,696
BRD2 MM1-S GEO Homo sapiens GSE43743 6,210
BRD2 foreskin NHM1-5 GEO Homo sapiens GSE94488 15,368
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks