CBFA2T3
Information CBFA2T3
- Description
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
- Full Name
CBFA2/RUNX1 partner transcriptional co-repressor 3
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 93,090
- Non-redundant peaks
- 76,158
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for CBFA2T3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CBFA2T3 | U-937 | GEO | Homo sapiens | GSE126953 | 16,458 | |||
| CBFA2T3 | Kasumi-1 | GEO | Homo sapiens | GSE126953 | 10,437 | |||
| CBFA2T3 | K-562 | GEO | Homo sapiens | GSE142227 | 11,242 | |||
| CBFA2T3 | K-562 | ENCODE | Homo sapiens | ENCSR697YLJ | 54,953 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |