CREB1

Information CREB1

Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Full Name

cAMP responsive element binding protein 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
22
Biotypes
12
Peaks
684,087
Non-redundant peaks
285,948

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
CREB-related factors
Sub Familly
CREB-like factors

Source TFClass

External IDs

NCBI Gene
1385
Official Gene Name
CREB1
JASPAR
MA0018
Ensembl
ENSG00000118260
UniProt
P16220
Genevisible
P16220
RefSeq
NM_001320793
Aliases
CREB; CREB-1
All peaks CREB1
Download BED file
Non redundant peaks CREB1
Download BED file
SEQUENCES CREB1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for CREB1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CREB1 GM23338 ENCODE Homo sapiens ENCSR214ZAV 25,689
CREB1 MDA-MB-134-VI E2 GEO Homo sapiens GSE109103 2,211
CREB1 MDA-MB-134-VI GEO Homo sapiens GSE109103 15,056
CREB1 MDA-MB-134-VI FI GEO Homo sapiens GSE109103 13,666
CREB1 LNCaP-abl SHCTR GEO Homo sapiens GSE63034 52,261
CREB1 LNCaP-abl GEO Homo sapiens GSE63034 27,248
CREB1 LNCaP-abl SHFOXA1 GEO Homo sapiens GSE63034 59,124
CREB1 LNCaP GEO Homo sapiens GSE63034 25,292
CREB1 WA01 ENCODE Homo sapiens ENCSR000BSN 50,522
CREB1 MCF-7 ENCODE Homo sapiens ENCSR620DUQ 76,539
CREB1 MCF-7 ENCODE Homo sapiens ENCSR897JAS 78,189
CREB1 K-562 ENCODE Homo sapiens ENCSR000BSO 24,546
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR112ALD 60,200
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR000BVL 31,789
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR331ORD 5,810
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRC 21,794
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRB 52,349
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRA 7,553
CREB1 Ishikawa ENCODE Homo sapiens ENCSR000BUR 6,870
CREB1 GM12878 ENCODE Homo sapiens ENCSR000BUF 41,618
CREB1 KG-1 DMSO GEO Homo sapiens GSE74928 481
CREB1 KG-1 XX65023 GEO Homo sapiens GSE74928 5,280
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks