E2F6

Information E2F6

Description

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Full Name

E2F transcription factor 6

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
5
Biotypes
4
Peaks
174,035
Non-redundant peaks
106,647

TF Classification

Super Class
Helix-turn-helix domains
Class
Fork head / winged helix factors
Familly
E2F-related factors
Sub Familly
E2F

Source TFClass

External IDs

NCBI Gene
1876
Official Gene Name
E2F6
JASPAR
MA0471
Ensembl
ENSG00000169016
UniProt
O75461
Genevisible
O75461
RefSeq
NM_001278275
Aliases
E2F-6
All peaks E2F6
Download BED file
Non redundant peaks E2F6
Download BED file
SEQUENCES E2F6
Download FASTA file
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Datasets Table for E2F6

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
E2F6 WA01 ENCODE Homo sapiens ENCSR000BSI 60,069
E2F6 K-562 ENCODE Homo sapiens ENCSR000BLI 44,271
E2F6 K-562 ENCODE Homo sapiens ENCSR000EWJ 44,212
E2F6 A-549 ENCODE Homo sapiens ENCSR000BTC 20,348
E2F6 HeLa-S3 ENCODE Homo sapiens ENCSR000EVK 5,135
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks