E2F6
Information E2F6
- Description
This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Full Name
E2F transcription factor 6
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 5
- Biotypes
- 4
- Peaks
- 174,035
- Non-redundant peaks
- 106,647
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Fork head / winged helix factors
- Familly
- E2F-related factors
- Sub Familly
- E2F
Source TFClass
External IDs
- NCBI Gene
- 1876
- Official Gene Name
- E2F6
- JASPAR
- MA0471
- Ensembl
- ENSG00000169016
- UniProt
- O75461
- Genevisible
- O75461
- RefSeq
- NM_001278275
- Aliases
- E2F-6
Datasets Table for E2F6
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| E2F6 | WA01 | ENCODE | Homo sapiens | ENCSR000BSI | 60,069 | |||
| E2F6 | K-562 | ENCODE | Homo sapiens | ENCSR000BLI | 44,271 | |||
| E2F6 | K-562 | ENCODE | Homo sapiens | ENCSR000EWJ | 44,212 | |||
| E2F6 | A-549 | ENCODE | Homo sapiens | ENCSR000BTC | 20,348 | |||
| E2F6 | HeLa-S3 | ENCODE | Homo sapiens | ENCSR000EVK | 5,135 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |