EOMES

Information EOMES

Description

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Full Name

eomesodermin

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
41,346
Non-redundant peaks
41,346

TF Classification

Super Class
Immunoglobulin fold
Class
T-Box factors
Familly
TBrain-related factors
Sub Familly
None

Source TFClass

External IDs

NCBI Gene
8320
Official Gene Name
EOMES
JASPAR
MA0800
Ensembl
ENSG00000163508
UniProt
O95936
Genevisible
O95936
RefSeq
NM_001278182
Aliases
TBR2
All peaks EOMES
Download BED file
Non redundant peaks EOMES
Download BED file
SEQUENCES EOMES
Download FASTA file
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Datasets Table for EOMES

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
EOMES hESC GEO Homo sapiens GSE26097 41,346
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks