EPAS1
Information EPAS1
- Description
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
- Full Name
endothelial PAS domain protein 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 8
- Biotypes
- 7
- Peaks
- 29,391
- Non-redundant peaks
- 25,846
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- PAS domain factors
- Sub Familly
- Ahr-like factors
Source TFClass
Datasets Table for EPAS1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| EPAS1 | macrophage | HYPO_IL | GEO | Homo sapiens | GSE43109 | 1,145 | ||
| EPAS1 | macrophage | NORMO_IL | GEO | Homo sapiens | GSE43109 | 83 | ||
| EPAS1 | 501-mel | GEO | Homo sapiens | GSE95280 | 10,688 | |||
| EPAS1 | PC-3 | hypoxia | GEO | Homo sapiens | GSE106305 | 12,386 | ||
| EPAS1 | K-562 | GEO | Homo sapiens | GSE123461 | 515 | |||
| EPAS1 | HUVEC-C | GEO | Homo sapiens | GSE89836 | 109 | |||
| EPAS1 | 786-O | GEO | Homo sapiens | GSE34871 | 1,150 | |||
| EPAS1 | ccRCC | GEO | Homo sapiens | GSE86092 | 3,315 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |