FANCL

Information FANCL

Description

This gene encodes a ubiquitin ligase that is a member of the Fanconi anemia complementation group (FANC). Members of this group are related by their assembly into a common nuclear protein complex rather than by sequence similarity. This gene encodes the protein for complementation group L that mediates monoubiquitination of FANCD2 as well as FANCI. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2018]

Full Name

FA complementation group L

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
5,604
Non-redundant peaks
5,604

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
55120
Official Gene Name
FANCL
JASPAR
Ensembl
ENSG00000115392
UniProt
Q9NW38
Genevisible
Q9NW38
RefSeq
NM_001114636
Aliases
FAAP43; FLJ10335; Pog
All peaks FANCL
Download BED file
Non redundant peaks FANCL
Download BED file
SEQUENCES FANCL
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for FANCL

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FANCL Jurkat GEO Homo sapiens GSE45864 5,604
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks