FOS

Information FOS

Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Full Name

Fos proto-oncogene, AP-1 transcription factor subunit

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
31
Biotypes
17
Peaks
630,073
Non-redundant peaks
298,257

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
Fos-related factors
Sub Familly
Fos factors

Source TFClass

External IDs

NCBI Gene
2353
Official Gene Name
FOS
JASPAR
MA1141
Ensembl
ENSG00000170345
UniProt
P01100
Genevisible
P01100
RefSeq
NM_005252
Aliases
AP-1; C-FOS; p55

External links
All peaks FOS
Download BED file
Non redundant peaks FOS
Download BED file
SEQUENCES FOS
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for FOS

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FOS MV4-11 GEO Homo sapiens GSE64862 7,883
FOS MV4-11 SHFLT3 GEO Homo sapiens GSE64862 4,146
FOS THP-1 eGFP-Pam3csk-0h GEO Homo sapiens GSE103477 193
FOS THP-1 eGFP-Pam3csk-4h GEO Homo sapiens GSE103477 6,061
FOS CFPAC-1 GEO Homo sapiens GSE119930 57,098
FOS leiomyoma PT967 GEO Homo sapiens GSE128230 8,681
FOS leiomyoma PT916 GEO Homo sapiens GSE128230 3,659
FOS leiomyoma PT1063 GEO Homo sapiens GSE128230 7,640
FOS leiomyoma PT886 GEO Homo sapiens GSE128230 21,153
FOS leiomyoma PT848 GEO Homo sapiens GSE128230 3,337
FOS MCF-7 ENCODE Homo sapiens ENCSR569XNP 66,999
FOS MCF-10A ENCODE Homo sapiens ENCSR000DON 75,894
FOS K-562 ENCODE Homo sapiens ENCSR000DKB 20,312
FOS K-562 ENCODE Homo sapiens ENCSR000FAI 14,761
FOS IMR-90 ENCODE Homo sapiens ENCSR124AIG 59,275
FOS Hep-G2 ENCODE Homo sapiens ENCSR177HDZ 25,964
FOS GM12878 ENCODE Homo sapiens ENCSR000EYZ 1,970
FOS endothelial umbilical-vein ENCODE Homo sapiens ENCSR000EVU 60,054
FOS CD4 fly-DNA_no-CD28 GEO Homo sapiens GSE116695 200
FOS CD4 GEO Homo sapiens GSE116695 10,715
FOS CD4 A-FOS_fly-DNA GEO Homo sapiens GSE116695 290
FOS CD4 fly-DNA GEO Homo sapiens GSE116695 1,348
FOS myometrium PT1063 GEO Homo sapiens GSE128230 15,440
FOS myometrium PT886 GEO Homo sapiens GSE128230 28,606
FOS myometrium PT967 GEO Homo sapiens GSE128230 27,408
FOS myometrium PT848 GEO Homo sapiens GSE128230 1,267
FOS myometrium PT916 GEO Homo sapiens GSE128230 8,661
FOS MG-63-3 GEO Homo sapiens GSE74230 4,293
FOS HeLa-S3 ENCODE Homo sapiens ENCSR000EZE 32,273
FOS HCT-116 A7A GEO Homo sapiens GSE152144 45,555
FOS MNNG-HOS GEO Homo sapiens GSE74230 8,937
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks