FOSL1

Information FOSL1

Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Full Name

FOS like 1, AP-1 transcription factor subunit

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
14
Biotypes
10
Peaks
233,758
Non-redundant peaks
118,331

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
Fos-related factors
Sub Familly
Fos factors

Source TFClass

External IDs

NCBI Gene
8061
Official Gene Name
FOSL1
JASPAR
MA1143
Ensembl
ENSG00000175592
UniProt
P15407
Genevisible
P15407
RefSeq
NM_001300844
Aliases
FRA; FRA1; fra-1
All peaks FOSL1
Download BED file
Non redundant peaks FOSL1
Download BED file
SEQUENCES FOSL1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for FOSL1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FOSL1 BT-549 GEO Homo sapiens GSE46166 25,418
FOSL1 BT-549 GEO Homo sapiens GSE112961 39,525
FOSL1 143B GEO Homo sapiens GSE74230 16,855
FOSL1 BJ fibroblast GEO Homo sapiens GSE114367 1,580
FOSL1 MDA-MB-231 GEO Homo sapiens GSE95303 28,780
FOSL1 MDA-MB-231 GEO Homo sapiens GSE132098 5,490
FOSL1 WA01 ENCODE Homo sapiens ENCSR000BNS 1,892
FOSL1 K-562 ENCODE Homo sapiens ENCSR000BMV 20,605
FOSL1 K-562 ENCODE Homo sapiens ENCSR239ZLZ 41,557
FOSL1 CD4-pos stimulated GEO Homo sapiens GSE87254 109
FOSL1 CD4-pos resting GEO Homo sapiens GSE87254 130
FOSL1 MG-63-3 GEO Homo sapiens GSE74230 9,954
FOSL1 HCT-116 ENCODE Homo sapiens ENCSR000BTE 27,997
FOSL1 MNNG-HOS GEO Homo sapiens GSE74230 13,866
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks