GABPA

Information GABPA

Description

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]

Full Name

GA binding protein transcription factor subunit alpha

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
24
Biotypes
15
Peaks
414,982
Non-redundant peaks
208,239

TF Classification

Super Class
Helix-turn-helix domains
Class
Tryptophan cluster factors
Familly
Ets-related factors
Sub Familly
Ets-like factors

Source TFClass

External IDs

NCBI Gene
2551
Official Gene Name
GABPA
JASPAR
MA0062
Ensembl
ENSG00000154727
UniProt
Q06546
Genevisible
Q06546
RefSeq
NM_001197297
Aliases
E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07
All peaks GABPA
Download BED file
Non redundant peaks GABPA
Download BED file
SEQUENCES GABPA
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for GABPA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
GABPA RWPE-1 GEO Homo sapiens GSE29808 2,684
GABPA DU145 GEO Homo sapiens GSE59021 3,116
GABPA VCaP R1881 GEO Homo sapiens GSE49091 56,726
GABPA VCaP ETOH GEO Homo sapiens GSE49091 52,956
GABPA VCaP GEO Homo sapiens GSE49091 54,951
GABPA THP-1 calcitriol_100nM_1d GEO Homo sapiens GSE98093 953
GABPA THP-1 EtOH_1d GEO Homo sapiens GSE98093 1,230
GABPA HeLa GEO Homo sapiens GSE31417 2,957
GABPA Hep-G2 GEO Homo sapiens GSE72082 16,630
GABPA WA01 ENCODE Homo sapiens ENCSR000BIW 31,200
GABPA SK-N-SH ENCODE Homo sapiens ENCSR000BTG 11,727
GABPA MCF-7 ENCODE Homo sapiens ENCSR000BUK 17,387
GABPA K-562 ENCODE Homo sapiens ENCSR000BLO 34,765
GABPA K-562 ENCODE Homo sapiens ENCSR290MUH 16,837
GABPA HL-60 ENCODE Homo sapiens ENCSR000BTK 8,471
GABPA Hep-G2 ENCODE Homo sapiens ENCSR269TNX 16,186
GABPA Hep-G2 ENCODE Homo sapiens ENCSR000BJK 8,878
GABPA A-549 ENCODE Homo sapiens ENCSR000BPY 19,994
GABPA liver ENCODE Homo sapiens ENCSR350ORK 6,911
GABPA liver ENCODE Homo sapiens ENCSR038GMB 21,571
GABPA MCF-7 GEO Homo sapiens GSE72082 1,759
GABPA GM12878 ENCODE Homo sapiens ENCSR000BGC 4,565
GABPA GM12878 ENCODE Homo sapiens ENCSR331HPA 12,636
GABPA HeLa-S3 ENCODE Homo sapiens ENCSR000BHS 9,892
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks