HDAC3
Information HDAC3
- Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Full Name
histone deacetylase 3
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 94,245
- Non-redundant peaks
- 89,498
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 8841
- Official Gene Name
- HDAC3
- JASPAR
- Ensembl
- ENSG00000171720
- UniProt
- O15379
- Genevisible
- O15379
- RefSeq
- NM_001355039
- Aliases
- HD3; KDAC3; RPD3; RPD3-2
Datasets Table for HDAC3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HDAC3 | VCaP | DHAT_2H | GEO | Homo sapiens | GSE28950 | 5,497 | ||
| HDAC3 | VCaP | ETOH | GEO | Homo sapiens | GSE28950 | 4,028 | ||
| HDAC3 | RH4 | DMSO-6H | GEO | Homo sapiens | GSE116344 | 70,534 | ||
| HDAC3 | K-562 | ENCODE | Homo sapiens | ENCSR024LKA | 4,994 | |||
| HDAC3 | AML | shaml1-eto | GEO | Homo sapiens | GSE131939 | 4,728 | ||
| HDAC3 | AML | GEO | Homo sapiens | GSE131939 | 4,464 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |