HDAC8

Information HDAC8

Description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Full Name

histone deacetylase 8

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
33,024
Non-redundant peaks
29,785

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
55869
Official Gene Name
HDAC8
JASPAR
Ensembl
ENSG00000147099
UniProt
Q9BY41
Genevisible
Q9BY41
RefSeq
NM_001166418
Aliases
KDAC8
All peaks HDAC8
Download BED file
Non redundant peaks HDAC8
Download BED file
SEQUENCES HDAC8
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for HDAC8

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HDAC8 K-562 ENCODE Homo sapiens ENCSR835TCD 22,871
HDAC8 K-562 ENCODE Homo sapiens ENCSR000DJZ 10,153
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks