HNF1B
Information HNF1B
- Description
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Full Name
HNF1 homeobox B
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 5
- Biotypes
- 5
- Peaks
- 111,912
- Non-redundant peaks
- 86,228
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Homeo domain factors
- Familly
- POU domain factors
- Sub Familly
- HNF1-like factors
Source TFClass
Datasets Table for HNF1B
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HNF1B | PDAC | GEO | Homo sapiens | GSE64557 | 28,260 | |||
| HNF1B | Hep-G2 | ENCODE | Homo sapiens | ENCSR127XTZ | 44,527 | |||
| HNF1B | PANC-1 | HNF1B-OE | GEO | Homo sapiens | GSE119930 | 27,815 | ||
| HNF1B | H9 | ENA | Homo sapiens | ERP004206 | 2,760 | |||
| HNF1B | foregut | GEO | Homo sapiens | GSE117136 | 8,550 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |