HSF1

Information HSF1

Description

The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Jul 2017]

Full Name

heat shock transcription factor 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
41
Biotypes
24
Peaks
218,848
Non-redundant peaks
105,056

TF Classification

Super Class
Helix-turn-helix domains
Class
Heat shock factors
Familly
HSF factors
Sub Familly
None

Source TFClass

External IDs

NCBI Gene
3297
Official Gene Name
HSF1
JASPAR
MA0486
Ensembl
ENSG00000284774
UniProt
Q00613
Genevisible
Q00613
RefSeq
NM_005526
Aliases
HSTF1
All peaks HSF1
Download BED file
Non redundant peaks HSF1
Download BED file
SEQUENCES HSF1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for HSF1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HSF1 MCF-7 GEO Homo sapiens GSE45852 1,016
HSF1 MCF-7 GEO Homo sapiens GSE38901 1,628
HSF1 MCF-7 hyperthermia-15min GEO Homo sapiens GSE137558 30,399
HSF1 MCF-7 estrogen-1h GEO Homo sapiens GSE137558 2,398
HSF1 BPE GEO Homo sapiens GSE38901 1,309
HSF1 BPE HEAT GEO Homo sapiens GSE38901 4,766
HSF1 ZR751 GEO Homo sapiens GSE38901 2,062
HSF1 HMLER GEO Homo sapiens GSE38901 233
HSF1 MO91 CHX_10UM GEO Homo sapiens GSE45852 19,649
HSF1 MO91 27A_20UM GEO Homo sapiens GSE45852 12,283
HSF1 MO91 GEO Homo sapiens GSE45852 28,736
HSF1 MO91 27A_100UM GEO Homo sapiens GSE45852 1,623
HSF1 NCI-H838 GEO Homo sapiens GSE38901 27,090
HSF1 hTERT-HME1 HEAT GEO Homo sapiens GSE38901 4,345
HSF1 hTERT-HME1 GEO Homo sapiens GSE38901 909
HSF1 WA09 heat-shock GEO Homo sapiens GSE105028 1,620
HSF1 BPLER GEO Homo sapiens GSE38901 2,689
HSF1 NCI-H441 GEO Homo sapiens GSE38901 1,181
HSF1 SK-BR-3 GEO Homo sapiens GSE38901 4,731
HSF1 SW620 GEO Homo sapiens GSE38901 1,554
HSF1 MCF-10A HEAT GEO Homo sapiens GSE38901 4,217
HSF1 MCF-10A GEO Homo sapiens GSE38901 465
HSF1 HT29 GEO Homo sapiens GSE38901 1,781
HSF1 BT-20 GEO Homo sapiens GSE38901 3,668
HSF1 colon tumor GEO Homo sapiens GSE38901 1,350
HSF1 MCF-7 ENCODE Homo sapiens ENCSR062HDL 648
HSF1 Hep-G2 ENCODE Homo sapiens ENCSR000EET 2,000
HSF1 MCF-7 CHX_10UM GEO Homo sapiens GSE45852 2,042
HSF1 GM12878 ENCODE Homo sapiens ENCSR009MBP 7,607
HSF1 breast tumor GEO Homo sapiens GSE38901 3,737
HSF1 NCI-H1703 GEO Homo sapiens GSE38901 445
HSF1 U2OS HEAT GEO Homo sapiens GSE60984 8,928
HSF1 U2OS HEAT_20 GEO Homo sapiens GSE60984 9,649
HSF1 HCT-15 GEO Homo sapiens GSE38901 1,098
HSF1 HCT-116 KOFBXW7 GEO Homo sapiens GSE57398 3,874
HSF1 HCT-116 KOFBXW7_HEAT GEO Homo sapiens GSE57398 382
HSF1 HCT-116 A10_43 GEO Homo sapiens GSE152144 6,826
HSF1 HCT-116 A9_43 GEO Homo sapiens GSE152144 1,269
HSF1 HCT-116 A8_43 GEO Homo sapiens GSE152144 8,153
HSF1 HCT-116 A9_37 GEO Homo sapiens GSE152144 221
HSF1 P12 GEO Homo sapiens GSE90716 267
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks