JUN

Information JUN

Description

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:14707112). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646). Involved in activated KRAS-mediated transcriptional activation of USP28 (By similarity). Binds to the USP28 promoter (By similarity). {ECO:0000250|UniProtKB:P05412, ECO:0000269|PubMed:14707112, ECO:0000269|PubMed:17210646}.(Source UnitProtKB).

Full Name

jun proto-oncogene

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
29
Biotypes
13
Peaks
701,170
Non-redundant peaks
244,624

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
16476
Official Gene Name
Jun
JASPAR
MGI
MGI:96646
Ensembl
ENSMUSG00000052684
UniProt
P05627
Genevisible
P05627
RefSeq
NM_010591
Aliases
AP-1; Junc; c-jun

External links
All peaks JUN
Download BED file
Non redundant peaks JUN
Download BED file
SEQUENCES JUN
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for JUN

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
JUN CH12-LX ENCODE Mus musculus ENCSR000ERO 12,173
JUN CD4-pos 6h GEO Mus musculus GSE132476 20,837
JUN CD4-pos vec GEO Mus musculus GSE132476 7,170
JUN CD4-pos 6h_KO GEO Mus musculus GSE132476 2,729
JUN hematopoietic-cell min-Dox GEO Mus musculus GSE79320 21,996
JUN hematopoietic-cell GEO Mus musculus GSE79320 4,938
JUN primary-hepatocyte IL-1 GEO Mus musculus GSE96767 8,359
JUN macrophage Pparg-KO GEO Mus musculus GSE111854 18,523
JUN macrophage veh GEO Mus musculus GSE111854 19,449
JUN macrophage veh_BL6 GEO Mus musculus GSE111854 11,242
JUN macrophage KLA-1h_BL6 GEO Mus musculus GSE111854 25,927
JUN mESC GEO Mus musculus GSE50776 601
JUN 3T3-L1 GEO Mus musculus GSE33821 5,580
JUN BMDM KLA_B6 GEO Mus musculus GSE109965 49,286
JUN BMDM KLA_PWK GEO Mus musculus GSE109965 77,448
JUN BMDM KLA GEO Mus musculus GSE109965 69,055
JUN BMDM PWK GEO Mus musculus GSE109965 59,975
JUN BMDM B6 GEO Mus musculus GSE109965 23,529
JUN BMDM Dex_LPS GEO Mus musculus GSE31796 106,601
JUN myoblast GEO Mus musculus GSE56077 61,558
JUN Th17 GEO Mus musculus GSE39756 33,139
JUN hematopoietic-cell plus-Dox GEO Mus musculus GSE79320 8,302
JUN BMDM GEO Mus musculus GSE109965 52,924
JUN BMDM SPRET GEO Mus musculus GSE109965 51,029
JUN BMDM LPS GEO Mus musculus GSE31796 7,550
JUN macrophage KLA-1h GEO Mus musculus GSE111854 25,383
JUN MEF GEO Mus musculus GSE50776 194
JUN CD8-pos GEO Mus musculus GSE54191 3,610
JUN C2C12 myoblast GEO Mus musculus GSE37525 8,874
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks