KLF5
Information KLF5
- Description
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
- Full Name
Kruppel like factor 5
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 17
- Biotypes
- 11
- Peaks
- 180,023
- Non-redundant peaks
- 88,579
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- C2H2 zinc finger factors
- Familly
- Three-zinc finger Krüppel-related factors
- Sub Familly
- Krüppel-like factors
Source TFClass
External IDs
- NCBI Gene
- 688
- Official Gene Name
- KLF5
- JASPAR
- MA0599
- Ensembl
- ENSG00000102554
- UniProt
- Q13887
- Genevisible
- Q13887
- RefSeq
- NM_001286818
- Aliases
- BTEB2; CKLF; IKLF
Datasets Table for KLF5
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| KLF5 | YCC-3 | GEO | Homo sapiens | GSE51705 | 2,475 | |||
| KLF5 | TE-5 | GEO | Homo sapiens | GSE143803 | 1,148 | |||
| KLF5 | HEK293 | D418N | GEO | Homo sapiens | GSE88976 | 19,508 | ||
| KLF5 | HEK293 | E419K | GEO | Homo sapiens | GSE88976 | 14,282 | ||
| KLF5 | HEK293 | E419Q | GEO | Homo sapiens | GSE88976 | 20,531 | ||
| KLF5 | HEK293 | GEO | Homo sapiens | GSE88976 | 15,092 | |||
| KLF5 | LoVo | PHASES | GEO | Homo sapiens | GSE51290 | 2,664 | ||
| KLF5 | LoVo | PHASEM | GEO | Homo sapiens | GSE51290 | 356 | ||
| KLF5 | AGS | GEO | Homo sapiens | GSE51705 | 775 | |||
| KLF5 | GP5D | GEO | Homo sapiens | GSE51234 | 15,264 | |||
| KLF5 | GP5D | SIRAD21 | GEO | Homo sapiens | GSE51234 | 377 | ||
| KLF5 | GM12878 | ENCODE | Homo sapiens | ENCSR974OFJ | 11,340 | |||
| KLF5 | ESO-26 | GEO | Homo sapiens | GSE132680 | 32,973 | |||
| KLF5 | HCC95 | E419Q | GEO | Homo sapiens | GSE88976 | 4,329 | ||
| KLF5 | HCC95 | GEO | Homo sapiens | GSE88976 | 10,739 | |||
| KLF5 | BICR | -31 | GEO | Homo sapiens | GSE88976 | 610 | ||
| KLF5 | KATO-III | GEO | Homo sapiens | GSE51705 | 27,560 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |