Kr

The gene Kruppel is referred to in FlyBase by the symbol DmelKr (CG3340, FBgn0001325). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:25226611..25231394. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; sequence-specific DNA binding. It is involved in the biological process described with 15 unique terms, many of which group under: negative regulation of cellular process; negative regulation of gene expression; stem cell fate commitment; embryonic hindgut morphogenesis; regulation of multicellular organismal development. 89 alleles are reported. The phenotypes of these alleles manifest in: eye-antennal disc; plasma membrane bounded cell projection; presumptive embryonic/larval digestive system; U neuron; embryonic/larval anterior Malpighian tubule. The phenotypic classes of alleles include: visible; lethal - all die before end of prepupal stage; viable; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-12 hour embryonic stages.

Kruppel

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6