MAX
Information MAX
- Description
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements (By similarity). {ECO:0000250|UniProtKB:P61244}.(Source UnitProtKB).
- Full Name
Max protein
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 6
- Peaks
- 62,763
- Non-redundant peaks
- 41,564
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for MAX
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MAX | fibroblast | GEO | Mus musculus | GSE119782 | 410 | |||
| MAX | CH12-LX | ENCODE | Mus musculus | ENCSR000ERL | 8,759 | |||
| MAX | myocyte | ENCODE | Mus musculus | ENCSR000AIL | 11,097 | |||
| MAX | mESC | GEO | Mus musculus | GSE48175 | 7,115 | |||
| MAX | MEL | ENCODE | Mus musculus | ENCSR000ETX | 10,689 | |||
| MAX | C2C12 | ENCODE | Mus musculus | ENCSR000AIO | 24,693 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |