MEF2B

Information MEF2B

Description

The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207. [provided by RefSeq, Jan 2014]

Full Name

myocyte enhancer factor 2B

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
6
Peaks
100,099
Non-redundant peaks
70,776

TF Classification

Super Class
alpha-Helices exposed by beta-structures
Class
MADS box factors
Familly
Regulators of differentiation
Sub Familly
MEF-2

Source TFClass

External IDs

NCBI Gene
100271849
Official Gene Name
MEF2B
JASPAR
MA0660
Ensembl
ENSG00000213999
UniProt
Q02080
Genevisible
Q02080
RefSeq
NM_001145785
Aliases
All peaks MEF2B
Download BED file
Non redundant peaks MEF2B
Download BED file
SEQUENCES MEF2B
Download FASTA file
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Datasets Table for MEF2B

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MEF2B OCI-Ly7 GEO Homo sapiens GSE69558 660
MEF2B KARPAS422 GEO Homo sapiens GSE69558 3,376
MEF2B GM12878 ENCODE Homo sapiens ENCSR177VFS 37,290
MEF2B DOHH2 GEO Homo sapiens GSE69558 7,239
MEF2B DLBCL GEO Homo sapiens GSE110682 16,142
MEF2B tonsil GEO Homo sapiens GSE110682 35,392
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks