NFKB2

Information NFKB2

Description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Full Name

nuclear factor kappa B subunit 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
25,373
Non-redundant peaks
25,373

TF Classification

Super Class
Immunoglobulin fold
Class
Rel homology region (RHR) factors
Familly
NF-kappaB-related factors
Sub Familly
NF-kappaB p50 subunit-like factors

Source TFClass

External IDs

NCBI Gene
4791
Official Gene Name
NFKB2
JASPAR
MA0778
Ensembl
ENSG00000077150
UniProt
Q00653
Genevisible
Q00653
RefSeq
NM_001077494
Aliases
CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52
All peaks NFKB2
Download BED file
Non redundant peaks NFKB2
Download BED file
SEQUENCES NFKB2
Download FASTA file
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Datasets Table for NFKB2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NFKB2 L1236 GEO Homo sapiens GSE63736 25,373
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks