NR4A1

Information NR4A1

Description

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Full Name

nuclear receptor subfamily 4 group A member 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
5
Biotypes
3
Peaks
83,773
Non-redundant peaks
69,197

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
Nuclear receptors with C4 zinc fingers
Familly
NGFI-B-related receptors (NR4)
Sub Familly
None

Source TFClass

External IDs

NCBI Gene
3164
Official Gene Name
NR4A1
JASPAR
MA1112
Ensembl
ENSG00000123358
UniProt
P22736
Genevisible
P22736
RefSeq
NM_001202233
Aliases
GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
All peaks NR4A1
Download BED file
Non redundant peaks NR4A1
Download BED file
SEQUENCES NR4A1
Download FASTA file
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Datasets Table for NR4A1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
NR4A1 MOLM-14 DHE GEO Homo sapiens GSE124963 27,135
NR4A1 Kasumi-1 GEO Homo sapiens GSE79491 33,665
NR4A1 K-562 ENCODE Homo sapiens ENCSR692RET 8,280
NR4A1 K-562 ENCODE Homo sapiens ENCSR130PDE 13,185
NR4A1 K-562 ENCODE Homo sapiens ENCSR000DJW 1,508
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks