NRF1
Information NRF1
- Description
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]
- Full Name
nuclear respiratory factor 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 28
- Biotypes
- 13
- Peaks
- 316,794
- Non-redundant peaks
- 90,751
TF Classification
- Super Class
- Yet undefined DNA-binding domains
- Class
- Uncharacterized
- Familly
- NRF
- Sub Familly
- None
Source TFClass
External IDs
- NCBI Gene
- 4899
- Official Gene Name
- NRF1
- JASPAR
- MA0506
- Ensembl
- ENSG00000106459
- UniProt
- Q16656
- Genevisible
- Q16656
- RefSeq
- NM_001040110
- Aliases
- ALPHA-PAL
Datasets Table for NRF1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NRF1 | MCF-7 | Ab_R157-1-3H1 | GEO | Homo sapiens | GSE97661 | 4,502 | ||
| NRF1 | Namalwa | GEO | Homo sapiens | GSE53133 | 6,890 | |||
| NRF1 | HCC1954 | GEO | Homo sapiens | GSE67867 | 27,894 | |||
| NRF1 | T-47D | HAEGIN2 | GEO | Homo sapiens | GSE59935 | 13,469 | ||
| NRF1 | HMEC-1 | GEO | Homo sapiens | GSE67867 | 30,350 | |||
| NRF1 | HeLa | dC9Sun-mCherry_TMEM206 | GEO | Homo sapiens | GSE107607 | 4,804 | ||
| NRF1 | HeLa | dC9Sun-D3A_TMEM206 | GEO | Homo sapiens | GSE107607 | 7,556 | ||
| NRF1 | Hep-G2 | GEO | Homo sapiens | GSE97661 | 9,022 | |||
| NRF1 | K-562 | Ab_R157-1-3D4 | GEO | Homo sapiens | GSE97661 | 19,792 | ||
| NRF1 | K-562 | Ab_R157-1-3H3 | GEO | Homo sapiens | GSE97661 | 16,384 | ||
| NRF1 | K-562 | Ab_R157-1-3H1 | GEO | Homo sapiens | GSE97661 | 8,992 | ||
| NRF1 | WA01 | ENCODE | Homo sapiens | ENCSR000ECC | 4,473 | |||
| NRF1 | SK-N-SH | ENCODE | Homo sapiens | ENCSR000EHZ | 9,505 | |||
| NRF1 | MCF-7 | ENCODE | Homo sapiens | ENCSR135ANT | 5,703 | |||
| NRF1 | K-562 | ENCODE | Homo sapiens | ENCSR494TDU | 17,678 | |||
| NRF1 | K-562 | ENCODE | Homo sapiens | ENCSR000EHH | 5,110 | |||
| NRF1 | K-562 | ENCODE | Homo sapiens | ENCSR837EYC | 25,494 | |||
| NRF1 | K-562 | ENCODE | Homo sapiens | ENCSR998AJK | 19,330 | |||
| NRF1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR000EEH | 2,217 | |||
| NRF1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR853ADA | 17,003 | |||
| NRF1 | MCF-7 | Ab_R157-1-3D4 | GEO | Homo sapiens | GSE97661 | 10,076 | ||
| NRF1 | GM12878 | ENCODE | Homo sapiens | ENCSR000DZO | 3,564 | |||
| NRF1 | HeLa-S3 | ENCODE | Homo sapiens | ENCSR000EDJ | 3,173 | |||
| NRF1 | HeLa-S3 | GEO | Homo sapiens | GSE108856 | 35,308 | |||
| NRF1 | HCT-116 | H1_sh1 | GEO | Homo sapiens | GSE152144 | 1,526 | ||
| NRF1 | HCT-116 | D4_NonT | GEO | Homo sapiens | GSE152144 | 1,708 | ||
| NRF1 | HCT-116 | H1_NonT | GEO | Homo sapiens | GSE152144 | 3,607 | ||
| NRF1 | HCT-116 | D4_sh1 | GEO | Homo sapiens | GSE152144 | 1,664 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |