OTX2
Information OTX2
- Description
This gene encodes a protein that belongs to the homeobox family of transcription factors. The encoded protein plays a role in the development and patterning of the head. This protein regulates development of the choroid plexuses in the brain affecting composition of cerebrospinal fluid in the developing brain and is thought to function in the development of sense organs in the embryo. In humans, mutations in this gene are associated with pituitary hormone deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]
- Full Name
orthodenticle homeobox 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 3
- Peaks
- 133,129
- Non-redundant peaks
- 100,091
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 18424
- Official Gene Name
- Otx2
- JASPAR
- MGI
- MGI:97451
- Ensembl
- ENSMUSG00000021848
- UniProt
- Genevisible
- RefSeq
- NM_144841
- Aliases
- E130306E05Rik
Datasets Table for OTX2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| OTX2 | subpallium | GEO | Mus musculus | GSE69724 | 16,279 | |||
| OTX2 | mESC | tetON | GEO | Mus musculus | GSE56098 | 23,525 | ||
| OTX2 | mESC | GEO | Mus musculus | GSE56098 | 31,905 | |||
| OTX2 | retina | GEO | Mus musculus | GSE54084 | 3,639 | |||
| OTX2 | retina | neural | GEO | Mus musculus | GSE54084 | 20,591 | ||
| OTX2 | mESC | DOX | GEO | Mus musculus | GSE56098 | 37,190 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |