PAX8

Information PAX8

Description

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

Full Name

paired box 8

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
8,768
Non-redundant peaks
8,314

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7849
Official Gene Name
PAX8
JASPAR
Ensembl
ENSG00000125618
UniProt
Q06710
Genevisible
Q06710
RefSeq
NM_003466
Aliases
All peaks PAX8
Download BED file
Non redundant peaks PAX8
Download BED file
SEQUENCES PAX8
Download FASTA file
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Datasets Table for PAX8

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PAX8 MCF-7 ENCODE Homo sapiens ENCSR949IWY 1,168
PAX8 K-562 ENCODE Homo sapiens ENCSR274CGK 2,079
PAX8 GM12878 ENCODE Homo sapiens ENCSR192AFN 1,840
PAX8 OVSAHO GEO Homo sapiens GSE79893 3,681
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks