POU2F3
Information POU2F3
- Description
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
- Full Name
POU class 2 homeobox 3
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 66,576
- Non-redundant peaks
- 66,576
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 25833
- Official Gene Name
- POU2F3
- JASPAR
- Ensembl
- ENSG00000137709
- UniProt
- Q9UKI9
- Genevisible
- Q9UKI9
- RefSeq
- NM_001244682
- Aliases
- Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a