PROX1
Information PROX1
- Description
The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
- Full Name
prospero homeobox 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 43,059
- Non-redundant peaks
- 42,885
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Homeo domain factors
- Familly
- HD-PROS factors
- Sub Familly
- None
Source TFClass
External IDs
- NCBI Gene
- 5629
- Official Gene Name
- PROX1
- JASPAR
- MA0794
- Ensembl
- ENSG00000117707
- UniProt
- Q92786
- Genevisible
- Q92786
- RefSeq
- NM_001270616
- Aliases
Datasets Table for PROX1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PROX1 | HUVEC-C | Prox1OE | GEO | Homo sapiens | GSE71230 | 1,941 | ||
| PROX1 | SW480 | GEO | Homo sapiens | GSE60390 | 41,118 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |