RBPJ
Information RBPJ
- Description
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
- Full Name
recombination signal binding protein for immunoglobulin kappa J region
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 18
- Biotypes
- 12
- Peaks
- 352,311
- Non-redundant peaks
- 165,328
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- Rel homology region (RHR) factors
- Familly
- CSL-related factors
- Sub Familly
- M
Source TFClass
External IDs
- NCBI Gene
- 3516
- Official Gene Name
- RBPJ
- JASPAR
- MA1116
- Ensembl
- ENSG00000168214
- UniProt
- Q06330
- Genevisible
- Q06330
- RefSeq
- NM_001363577
- Aliases
- AOS3; CBF1; IGKJRB; IGKJRB1; KBF2; RBP-J; RBPJK; RBPSUH; SUH; csl
Datasets Table for RBPJ
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RBPJ | GSC8-11 | dasatinib | GEO | Homo sapiens | GSE74557 | 27,245 | ||
| RBPJ | GSC8-11 | GEO | Homo sapiens | GSE74557 | 4,005 | |||
| RBPJ | GSC8-11 | 12d-das | GEO | Homo sapiens | GSE74557 | 31,718 | ||
| RBPJ | GIC | GEO | Homo sapiens | GSE79734 | 11,225 | |||
| RBPJ | NHEK | GEO | Homo sapiens | GSE29498 | 33,006 | |||
| RBPJ | MUTUL | GEO | Homo sapiens | GSE75503 | 26,919 | |||
| RBPJ | LCL | GEO | Homo sapiens | GSE75503 | 25,232 | |||
| RBPJ | THP-6 | shCtrl | GEO | Homo sapiens | GSE138516 | 11,098 | ||
| RBPJ | THP-6 | shEts1 | GEO | Homo sapiens | GSE138516 | 6,945 | ||
| RBPJ | HUVEC-C | VEGF_12h | GEO | Homo sapiens | GSE109625 | 798 | ||
| RBPJ | CUTLL1 | GEO | Homo sapiens | GSE29600 | 10,499 | |||
| RBPJ | MDA-MB-157 | GEO | Homo sapiens | GSE116868 | 14,832 | |||
| RBPJ | MDA-MB-157 | GSI | GEO | Homo sapiens | GSE116868 | 11,458 | ||
| RBPJ | HCC1599 | GSI | GEO | Homo sapiens | GSE116871 | 23,228 | ||
| RBPJ | HCC1599 | GEO | Homo sapiens | GSE116871 | 26,160 | |||
| RBPJ | HKC | GEO | Homo sapiens | GSE102761 | 556 | |||
| RBPJ | SCC | 4h | GEO | Homo sapiens | GSE156486 | 49,401 | ||
| RBPJ | SCC | 0h | GEO | Homo sapiens | GSE156486 | 37,986 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |