SETDB1
Information SETDB1
- Description
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
- Full Name
SET domain bifurcated histone lysine methyltransferase 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 149,615
- Non-redundant peaks
- 82,533
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 9869
- Official Gene Name
- SETDB1
- JASPAR
- Ensembl
- ENSG00000143379
- UniProt
- Q15047
- Genevisible
- Q15047
- RefSeq
- NM_001145415
- Aliases
- ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; TDRD21
Datasets Table for SETDB1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SETDB1 | WN8532 | GEO | Homo sapiens | GSE36579 | 5,282 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000EWD | 6,281 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000EWI | 19,710 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000AUT | 500 | |||
| SETDB1 | U2OS | ENCODE | Homo sapiens | ENCSR000EYD | 59,383 | |||
| SETDB1 | HEK293 | ENCODE | Homo sapiens | ENCSR348AGV | 58,459 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |