SIRT6
Information SIRT6
- Description
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
- Full Name
sirtuin 6
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 5
- Biotypes
- 3
- Peaks
- 67,587
- Non-redundant peaks
- 63,927
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 51548
- Official Gene Name
- SIRT6
- JASPAR
- Ensembl
- ENSG00000077463
- UniProt
- Q8N6T7
- Genevisible
- Q8N6T7
- RefSeq
- NM_001193285
- Aliases
Datasets Table for SIRT6
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SIRT6 | SK-MEL-239 | L-C-B | GEO | Homo sapiens | GSE102813 | 50,961 | ||
| SIRT6 | SK-MEL-239 | SIRT6-2-7 | GEO | Homo sapiens | GSE102813 | 3,797 | ||
| SIRT6 | WA01 | ENCODE | Homo sapiens | ENCSR000AUS | 1,531 | |||
| SIRT6 | K-562 | ENCODE | Homo sapiens | ENCSR000AUB | 9,080 | |||
| SIRT6 | K-562 | ENCODE | Homo sapiens | ENCSR000DOH | 2,218 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |