SOX2

Information SOX2

Description

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Full Name

SRY-box transcription factor 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
28
Biotypes
18
Peaks
348,102
Non-redundant peaks
213,094

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6657
Official Gene Name
SOX2
JASPAR
Ensembl
ENSG00000181449
UniProt
P48431
Genevisible
P48431
RefSeq
NM_003106
Aliases
ANOP3; MCOPS3

External links
All peaks SOX2
Download BED file
Non redundant peaks SOX2
Download BED file
SEQUENCES SOX2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SOX2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SOX2 HNSC GEO Homo sapiens GSE69479 74,391
SOX2 RENVM GEO Homo sapiens GSE49404 38,149
SOX2 RENVM SHSOX2 GEO Homo sapiens GSE49404 4,497
SOX2 HCC2814 GEO Homo sapiens GSE137459 4,453
SOX2 LK2 DNp63 GEO Homo sapiens GSE137459 9,980
SOX2 LK2 GFP GEO Homo sapiens GSE137459 49,315
SOX2 LK2 GEO Homo sapiens GSE137459 2,922
SOX2 glioma stem GEO Homo sapiens GSE67282 3,859
SOX2 KNS-62 GEO Homo sapiens GSE137459 4,974
SOX2 TT GEO Homo sapiens GSE46837 10,180
SOX2 NCI-H520 GEO Homo sapiens GSE137459 4,553
SOX2 H9 GEO Homo sapiens GSE46837 3,216
SOX2 hESC GEO Homo sapiens GSE69479 2,352
SOX2 hESC GEO Homo sapiens GSE18292 18,963
SOX2 HCC95 GEO Homo sapiens GSE137459 11,552
SOX2 KYSE-70 GEO Homo sapiens GSE46837 6,837
SOX2 hiPSC GEO Homo sapiens GSE67282 6,644
SOX2 hiPSC KDP53_INHI GEO Homo sapiens GSE67282 6,197
SOX2 hiPSC KDP53 GEO Homo sapiens GSE67282 5,025
SOX2 hiPSC INHI GEO Homo sapiens GSE67282 3,238
SOX2 hiPSC 3s2 GEO Homo sapiens GSE81899 879
SOX2 hiPSC GEO Homo sapiens GSE56567 64,222
SOX2 OSKM GEO Homo sapiens GSE81899 5,507
SOX2 OSvK GEO Homo sapiens GSE81899 262
SOX2 OSvKM GEO Homo sapiens GSE81899 256
SOX2 OSK GEO Homo sapiens GSE81899 1,236
SOX2 NPC GEO Homo sapiens GSE122631 4,225
SOX2 NPC R1159Q GEO Homo sapiens GSE122631 218
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks