SPDEF
Information SPDEF
- Description
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Full Name
SAM pointed domain containing ETS transcription factor
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 67,189
- Non-redundant peaks
- 63,402
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 25803
- Official Gene Name
- SPDEF
- JASPAR
- MA0686
- Ensembl
- ENSG00000124664
- UniProt
- O95238
- Genevisible
- O95238
- RefSeq
- NM_001252294
- Aliases
- PDEF; bA375E1.3
Datasets Table for SPDEF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SPDEF | MCF-7 | ENCODE | Homo sapiens | ENCSR042GSX | 55,635 | |||
| SPDEF | A-549 | GEO | Homo sapiens | GSE86957 | 11,554 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |