TBX5

Information TBX5

Description

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Full Name

T-box transcription factor 5

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
8
Biotypes
3
Peaks
172,663
Non-redundant peaks
73,700

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6910
Official Gene Name
TBX5
JASPAR
MA0807
Ensembl
ENSG00000089225
UniProt
Q99593
Genevisible
Q99593
RefSeq
NM_000192
Aliases
HOS
All peaks TBX5
Download BED file
Non redundant peaks TBX5
Download BED file
SEQUENCES TBX5
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for TBX5

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TBX5 hiPSC GEO Homo sapiens GSE81585 20,664
TBX5 G296S 4 GEO Homo sapiens GSE85628 30,701
TBX5 G296S 2 GEO Homo sapiens GSE85628 26,769
TBX5 G296S GEO Homo sapiens GSE85628 26,785
TBX5 cardiomyocyte GEO Homo sapiens GSE85628 14,856
TBX5 cardiomyocyte 7 GEO Homo sapiens GSE85628 16,589
TBX5 cardiomyocyte 5 GEO Homo sapiens GSE85628 21,456
TBX5 cardiomyocyte 1 GEO Homo sapiens GSE85628 14,843
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks