TFAP2A
Information TFAP2A
- Description
This gene is a member of the activator protein 2 (AP-2) transcription factor family. The protein encoded by this gene can act as both an activator and repressor of gene transcription, and plays an important role in early embryogenesis, specifically in cranial development. This protein forms both homodimers and heterodimers, and binds to a GC-rich consensus sequence found in some promoters and enhancers. Disruption of this gene causes perinatal death, with neural tube, craniofacial, and limb mesenchyme defects. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]
- Full Name
transcription factor AP-2, alpha
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 22,768
- Non-redundant peaks
- 22,768
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 21418
- Official Gene Name
- Tfap2a
- JASPAR
- MGI
- MGI:104671
- Ensembl
- ENSMUSG00000021359
- UniProt
- Genevisible
- RefSeq
- NM_011547
- Aliases
- AP-2; AP-2 alpha; AP2alpha; Ap-2 (a); Ap2; Ap2tf; Tcfap2a
Datasets Table for TFAP2A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TFAP2A | melanocyte | GEO | Mus musculus | GSE72953 | 22,768 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |