TFAP2A
Information TFAP2A
- Description
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
- Full Name
transcription factor AP-2 alpha
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 60,320
- Non-redundant peaks
- 45,781
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-span-helix factors (bHSH)
- Familly
- AP-2
- Sub Familly
- None
Source TFClass
External IDs
- NCBI Gene
- 7020
- Official Gene Name
- TFAP2A
- JASPAR
- MA0872
- Ensembl
- ENSG00000137203
- UniProt
- P05549
- Genevisible
- P05549
- RefSeq
- NM_001032280
- Aliases
- AP-2; AP-2alpha; AP2TF; BOFS; TFAP2
Datasets Table for TFAP2A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TFAP2A | MCF-7 | E2 | GEO | Homo sapiens | GSE60270 | 33,495 | ||
| TFAP2A | WA09 | GEO | Homo sapiens | GSE105081 | 16,872 | |||
| TFAP2A | MCF-7 | GEO | Homo sapiens | GSE60270 | 9,953 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |