TP73
Information TP73
- Description
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
- Full Name
tumor protein p73
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 40,601
- Non-redundant peaks
- 29,614
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- p53 domain factors
- Familly
- p53-related factors
- Sub Familly
- None
Source TFClass
External IDs
- NCBI Gene
- 7161
- Official Gene Name
- TP73
- JASPAR
- MA0861
- Ensembl
- ENSG00000078900
- UniProt
- O15350
- Genevisible
- O15350
- RefSeq
- NM_001126240
- Aliases
- P73
Datasets Table for TP73
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TP73 | TA | SaOS-2 | GEO | Homo sapiens | GSE15780 | 15,534 | ||
| TP73 | DELTANP | SaOS-2 | GEO | Homo sapiens | GSE15780 | 23,707 | ||
| TP73 | GM12878 | GEO | Homo sapiens | GSE97661 | 1,360 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |