ZEB1

Information ZEB1

Description

This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]

Full Name

zinc finger E-box binding homeobox 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
8
Peaks
155,380
Non-redundant peaks
110,495

TF Classification

Super Class
Helix-turn-helix domains
Class
Homeo domain factors
Familly
HD-ZF factors
Sub Familly
ZEB

Source TFClass

External IDs

NCBI Gene
6935
Official Gene Name
ZEB1
JASPAR
MA0103
Ensembl
ENSG00000148516
UniProt
P37275
Genevisible
P37275
RefSeq
NM_001128128
Aliases
AREB6; BZP; DELTAEF1; FECD6; NIL-2-A; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A

External links
All peaks ZEB1
Download BED file
Non redundant peaks ZEB1
Download BED file
SEQUENCES ZEB1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for ZEB1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ZEB1 RKO GEO Homo sapiens GSE88734 10,207
ZEB1 NCI-H1975 resistant GEO Homo sapiens GSE106896 11,175
ZEB1 NCI-H1975 GEO Homo sapiens GSE106896 4,067
ZEB1 PDAC GEO Homo sapiens GSE64557 18,996
ZEB1 Hep-G2 ENCODE Homo sapiens ENCSR000BVN 13,172
ZEB1 HEK293 ENCODE Homo sapiens ENCSR909HMT 22,109
ZEB1 GM12878 ENCODE Homo sapiens ENCSR000BND 50,629
ZEB1 MIA-PaCa-2 WT GEO Homo sapiens GSE88734 1,125
ZEB1 MIA-PaCa-2 GEO Homo sapiens GSE88734 3,949
ZEB1 neuron bipolar_doxy_4d ENCODE Homo sapiens ENCSR418KUS 19,951
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks