ZNF384

Information ZNF384

Description

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]

Full Name

zinc finger protein 384

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
109,236
Non-redundant peaks
83,673

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
C2H2 zinc finger factors
Familly
More than 3 adjacent zinc finger factors
Sub Familly
ZNF362-like factors

Source TFClass

External IDs

NCBI Gene
171017
Official Gene Name
ZNF384
JASPAR
MA1125
Ensembl
ENSG00000126746
UniProt
Q8TF68
Genevisible
Q8TF68
RefSeq
NM_001039920
Aliases
CAGH1A; CIZ; NMP4
All peaks ZNF384
Download BED file
Non redundant peaks ZNF384
Download BED file
SEQUENCES ZNF384
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for ZNF384

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ZNF384 K-562 ENCODE Homo sapiens ENCSR000EFP 39,284
ZNF384 Hep-G2 ENCODE Homo sapiens ENCSR101FJU 46,070
ZNF384 HEK293T ENCODE Homo sapiens ENCSR882ICT 19,184
ZNF384 GM12878 ENCODE Homo sapiens ENCSR000DYP 4,698
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks