aop

The gene anterior open is referred to in FlyBase by the symbol Dmelaop (CG3166, FBgn0000097). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:2156484..2178754. Its molecular function is described by 7 unique terms, many of which group under: binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific double-stranded DNA binding; DNA binding. It is involved in the biological process described with 27 unique terms, many of which group under: regulation of cell fate specification; ERBB signaling pathway; multicellular organism aging; positive regulation of metabolic process; cellular response to fibroblast growth factor stimulus. 106 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; male germline cell; tracheal tip cell; embryonic cardioblast; dorsal mesothorax. The phenotypic classes of alleles include: increased mortality during development; partially lethal; lethal; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages.

anterior open

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6